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MAMO1 Study

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Despite the availability of multiple public health interventions, approximately 608,000 malaria deaths were recorded in 2022, with the majority of these deaths occurring in children under 5 years of age.…
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IMPALA

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Improving HIV Outcomes in Africa with Long-acting Antiretrovirals Long-acting (LA) injectable therapy for the treatment of Human Immunodeficiency Virus (HIV)-1 infection offers a reduced dosing frequency and an additional option…
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ENRICH+

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Neurocognitive impairment (NCI) is one of the most prevalent and deleterious complications observed in adolescents and young adults (AYA) with perinatally acquired HIV (PHIV), even despite viral suppression. There are…
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D3 /Penta 21

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Life-long ART presents new challenges of treatment fatigue and long-term toxicities, and the growing population in need of ART pose critical public health questions over the long-term financial sustainability of…
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CITU512

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This is a global first-in-human randomized Phase I/II clinical study of ITU512, to assess the safety, tolerability, PK, PD and preliminary food effect of ITU512 in adult healthy participants, and…
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CAPRI

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The CAPRI study will evaluate the reproducibility of Cascade Primed Cells with Apheretic collected Autologous PBMCs in Uganda, and test the effect of the reproduced CAPRI cells on Lung and…
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BREATHER-Plus Study

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Adolescents have poorer treatment outcomes including higher loss to follow-up, lower treatment adherence, poorer virological suppression and higher mortality than older people living with HIV. Some of the adherence challenges…
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Protocol 0106

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It is a Phase 2/3, Open-Label Study to confirm the dose of elvitegravir/cobicistat/emtricitabin e/tenofoviralafenamide (E/C/F/TAF) single tablet regimen (STR) in HIV-1 infected, antiretroviral (ARV) treatment naive adolescents and evaluate the…
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